SARS-CoV-2 Neutralizing antibody Test Cassette

Kuongororwa kwemhando yeCoronavirus Chirwere 2019 (2019-nCOV kana COVID -19) inodzivirira antibody muserum yemunhu/plasma/ropa rose.

Yehunyanzvi In Vitro Diagnostic Shandisa Chete

【ZVIRI KUSHANDISWA】

Iyo SARS-CoV-2 Neutralizing antibody Test Cassette inokurumidza chromatographic

immunoassay yekuonekwa kwemhando yekusaudzira antibody yeCoronavirus Chirwere 2019 muropa revanhu rose, serum, kana plasma serubatsiro muKuongorora mazinga emunhu anti-novel coronavirus neutralizing antibody titer.

mhuka dzinoyamwisa.The genus γ inonyanya kukonzera zvirwere zveshiri.CoV inonyanya kutapuriranwa kuburikidza nekubata zvakananga nezvinobuda kana kuburikidza neaerosols nemadonhwe. Pane zvakare humbowo hwekuti inogona kutapurirwa kuburikidza nefecal-oral nzira.

Severe acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, kana 2019-nCoV) hutachiona hwakaputirwa husina-segmented positive-sense RNA virus. Ndiyo honzeri yechirwere chekoronavirus 2019 (COVID-19), icho chinotapukira muvanhu.

SARS-CoV-2 ine akati wandei mapuroteni anosanganisira spike (S), hamvuropu (E), membrane (M) uye nucleocapsid (N). Iyo spike protein (S) ine receptor binding domain (RBD), iyo ine basa rekuziva iyo cell surface receptor, angiotensin inoshandura enzyme-2 (ACE2). Inowanikwa kuti iyo RBD yeSARS-CoV-2 S protein inopindirana zvine simba nemunhu ACE2 receptor inotungamira kune endocytosis mumaseru anotambira emukati memapapu akadzika uye hutachiona kudzokorora.

Kutapukira neSARS-CoV-2 kunotanga mhinduro yekudzivirira, iyo inosanganisira kugadzirwa kwemasoja ekudzivirira chirwere muropa. Masoja ekudzivirira akavanzika anopa dziviriro kuzvirwere zvenguva yemberi kubva kumavhairasi, nekuti anoramba ari muhurongwa hwekutenderera kwemwedzi kusvika kumakore mushure mekutapukirwa uye anosunga nekukurumidza uye zvakasimba kune pathogen kuvharira kupindira kwemasero uye kudzokorora. Masoja ekudzivirira chirwere anonzi neutralizing antibodies.

【 KUCHENGA UYE KUGADZIRIRA ZVINHU 】

1.The SARS-CoV-2 Neutralizing antibody Test Cassette yakagadzirirwa kushandiswa neropa revanhu rose, serum kana plasma mienzaniso chete.

2.Zviratidzo zvakajeka chete, zvisina-hemolyzed zvinokurudzirwa kushandiswa nemuedzo uyu. Serum kana plasma inofanira kupatsanurwa nekukurumidza sezvinobvira kudzivirira hemolysis.

3.Ita kuedza pakarepo mushure mekuunganidza kwemuenzaniso. Usasiye zvienzaniso pane tembiricha yekamuri kwenguva yakareba. Serum uye plasma mienzaniso inogona kuchengetwa pa 2-8 ° C kwemazuva matatu. Nekuchengetedza kwenguva refu, serum kana plasma samples inofanira kuchengetwa pasi-20 ° C. Ropa rose rakatorwa ne venipuncture rinofanira kuchengetwa pa 2-8 ° C kana kuedza kuchizoitwa mukati memazuva maviri mushure mekuunganidza. Usaomesa ropa rose. mienzaniso. Ropa rose raunganidzwa nemunwe rinofanira kuongororwa nekukurumidza.

4.Midziyo ine anticoagulants yakadai seEDTA,citrate,kana heparin inofanira kushandiswa pakuchengetedza ropa rose.Unza mienzaniso kune tembiricha yekamuri usati waedzwa.

5.Mienzaniso yechando inofanira kunyungudutswa zvachose uye yakasanganiswa zvakanaka isati yaedzwa.Dzivisa kuomesa nechando.

uye kunyungudutswa kwemifananidzo.

6.Kana zvienzaniso zvichizotumirwa, zvitakure maererano nemitemo yese yekufambisa.

etiological agents.

7.Icteric, lipemic, hemolyzed, kupisa kunorapwa uye sera yakasvibiswa inogona kukonzera mhedzisiro isina kururama.

8.Paunounganidza chigunwe chetsvimbo yeropa ine lancet uye doro padhi, Ndokumbira urase donhwe rekutanga re

ropa rose.

1. Hunza homwe patembiricha yemumba usati wavhura.Bvisa mudziyo wekuyedza kubva muhomwe yakavharwa woishandisa nekukasika.

2. Isa mudziyo wekuedza panzvimbo yakachena uye yakaenzana.

YeSerum kana Plasma Zviyero: Uchishandisa iyo Micropipette, uye kuendesa 5ul serum/plasma kumuenzaniso mutsime webvunzo mudziyo, wobva wawedzera 2 donho rebuffer, uye tanga timer.

YeRopa Rakazara (Venipuncture/Fingerstick) Mienzaniso: Baya chigunwe chako wosvina chigunwe chako zvinyoro nyoro, shandisa iyo yakapihwa yepurasitiki pipette kuyamwa 10ul yeropa rakazara kumutsara gumi wepipette yepurasitiki inoraswa, uye woiendesa kune yemuenzaniso gomba rechishandiso chekuyedza (kana vhoriyamu yese yeropa ichipfuura mucherechedzo, Ndokumbira usunungure yakawandisa ropa rose mupipette), wobva wawedzera 2 donhwe rebuffer, wotanga timer. Ongorora: Zvimiro zvinogona zvakare kuiswa uchishandisa micropipette.

3. Mirira kuti mitsetse ine mavara ionekwe.Verenga zvabuda pamaminitsi gumi nemashanu.Usadudzire zvawanikwa mushure memaminitsi makumi maviri.